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Zytiga®, also known as” Abirapro, Abiratas, Abretone” is a CYP17 inhibitor indicated in combination with prednisone for the treatment of patients with metastatic castration-resistant prostate cancer. Zytiga is Abiraterone‘s US name manufactured by Janssen Biotech. Intas Pharmaceuticals markets the drug under the trade name Abiratas, Glenmark markets the medicine under the trade name Abirapro. Cadila Pharmaceuticals as Abretone.
DOSAGE AND ADMINISTRATION
Recommended dose: ZYTIGA 1,000 mg (two 500 mg tablets or four 250 mg tablets) administered orally once daily in combination with prednisone 5 mg administered orally twice daily. ZYTIGA must be taken on an empty stomach. No food should be consumed for at least two hours before the dose of ZYTIGA is taken and for at least one hour after the dose of ZYTIGA is taken. The tablets should be swallowed whole with water. Do not crush or chew tablets.
1.For patients with baseline moderate hepatic impairment (Child-Pugh Class B), reduce the ZYTIGA starting dose to 250 mg once daily.
2.For patients who develop hepatotoxicity during treatment, hold ZYTIGA until recovery. Retreatment may be initiated at a reduced dose. ZYTIGA should be discontinued if patients develop severe hepatotoxicity.
|Warnings||Don't take the drug without consulting a qualified doctor or physician.|
|Suggested use||Follow the doctor's advice|
|Delivery & Returns||10-20 days|