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Hernix (Neratinib) ‘s brand name is Nerlynx ® by Puma Biotechnology. Hernix (Nerlynx) is a generic is a kinase inhibitor indicated for breast cancer from Beacon, which is a listed and the largest generic pharmaceutical manufacturer in Bangladesh.
Neratinib is a kinase inhibitor indicated for the extended adjuvant treatment of adult patients with early stage HER2-overexpressed/amplified breast cancer, to follow adjuvant trastuzumab-based therapy.
Generic Nerlynx (Neratinib) Cost & Price:
Generic Nerlynx (Neratinib)’s price is only 15% of the brand Nerlynx ® in United States and Canada.
DOSAGE AND ADMINISTRATION
1. Antidiarrheal prophylaxis: Initiate loperamide with the first dose of Hernix (Neratinib) and continue during first 2 cycles (56 days) of treatment. Instruct patients to maintain 1-2 bowel movements per day and on how to use antidiarrheal treatment regimens
2.Recommended dose: 240 mg (6 tablets) given orally once daily with food, continuously for one year.
3.Dose interruptions and/or dose reductions are recommended based on individual safety and tolerability.
3.Hepatic Impairment: Reduce starting dose to 80 mg in patients with severe hepatic impairment.
Hernix (Neratinib) Side Effects：
Diarrhea. Diarrhea is a common side effect of HERNIX (NERATINIB) , but it can also be severe. You may lose too much body salts and fluids, and get dehydrated. Your healthcare provider should prescribe the medicine loperamide for you during your first 2 months (56 days) of HERNIX (NERATINIB) and then as needed. To help prevent or reduce diarrhea:
o You should start taking loperamide with your first dose of HERNIX (NERATINIB). o Keep taking loperamide during the first 2 months (56 days) of HERNIX (NERATINIB) treatment and then as needed. Your
healthcare provider will tell you exactly how much and how often to take loperamide. o Always take loperamide exactly as your healthcare provider tells you. o While taking loperamide, you and your healthcare provider should try to keep the number of bowel movements
that you have at 1 or 2 bowel movements each day.
o Tell your healthcare provider if you have more than 2 bowel movements in 1 day, or you have diarrhea that does not go away.
o Call your healthcare provider right away, as instructed, if you have severe diarrhea or if you have diarrhea along with weakness, dizziness, or fever.
o Your healthcare provider may also need to give you other medicines to manage diarrhea if loperamide does not work well enough.
o After2months(56days) of treatment with HERNIX (NERATINIB) ,follow your health care provider’s instructions about taking loperamide as needed to control diarrhea.
Your healthcare provider may change your dose of HERNIX (NERATINIB) , temporarily stop or completely stop HERNIX (NERATINIB) if needed to manage your diarrhea.
For more Prescribing information，please check the → “FDA Prescribing Information”.
|Package Quantity||180 Tablets|
|Warnings||Don't take the drug without consulting a qualified doctor or physician|
|Suggested use||Follow the doctor's advice|
|Delivery & Returns||7-14 Days|